In the midst of the early days of the COVID-19 pandemic, Grey Sloan Memorial and its surgeons' lives have been turned upside down. The season 17 premiere picks up one month into the pandemic, and it's all-hands-on-deck as Meredith, Bailey and the rest of the Grey Sloan doctors find themselves on the frontlines of a new era. Meanwhile, an unintentionally started fire has first responders from Station 19 bringing patients into the hospital for treatment.