Deep blue sea conceals many dangers, but it is in its depths are scientists hydrolab "Bubble", which are exploring and developing the newest drug to cure Alzheimer's disease. Using substances from the brain, Dr. Susan Mcalister creates a unique whey. But extracted material is very small, due to the small size of the brain at the sharks.
To increase brain predators, scientists have resorted to genetic engineering, which leads to significant brain development and intelligence, making several experimental animals in cruel, calculating and ruthless murderers. Now the sharks are able not only to think but to outsmart the people from the "Akvatiki" come in Horror, because they are cut off from the world. Without any contact, the heroes of the film are forced to survive within the walls of the underwater laboratory, which is being attacked by an angry predators.